Gene description for YWHAQ
Gene name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Gene symbol YWHAQ
Other names/aliases 14-3-3
1C5
HS1
Species Homo sapiens
 Experiment description of studies that identified YWHAQ in Neuroblastoma cells

1
Experiment ID556
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24069378   
OrganismHomo sapiens
Experiment descriptionProteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.
AuthorsMarimpietri D, Petretto A, Raffaghello L, Pezzolo A, Gagliani C, Tacchetti C, Mauri P, Melioli G, Pistoia V.
Journal name PLoS One
Publication year2013
SampleNeuroblastoma cells
Sample name HTLA-230
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130101: EV-METRIC:38%, 14%

2
Experiment ID903
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25053844   
OrganismHomo sapiens
Experiment descriptionActivity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons
AuthorsGoldie BJ, Dun MD, Lin M, Smith ND, Verrills NM, Dayas CV, Cairns MJ.
Journal name Nucleic Acids Res
Publication year2014
SampleNeuroblastoma cells
Sample nameSH-SY5Y
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140076: EV-METRIC:38%

3
Experiment ID1153
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22057275   
OrganismHomo sapiens
Experiment descriptionExosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.
AuthorsSaman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, Hall GF.
Journal name J Biol Chem
Publication year2012
SampleNeuroblastoma cells
Sample nameM1C cells (inducibly expressing wild-type human tau
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120107: EV-METRIC:11%, 11%

<